Noxitril Warnings

By: Dr. Brian Straub, Pharm.D.

Possible Prescription Drug Interactions and Medical Warnings For Noxitril

Noxitril is a very popular testosterone booster that has been on the market for several years now.

I get a lot of questions regarding whether or not you can take it with various medical conditions and prescription medications.

We’ve partnered with a pharmacist who has answered these questions below.

* Click Here for a full list of potential drug interactions.

Can I take Noxitril if I have high blood pressure?

  • There appear to be no negative interactions with the medications themselves for those with high blood pressure, but some ingredients may lower blood pressure.

    If you are taking blood pressure medications, use caution, as this supplement may also lower blood pressure.

Can I take Noxitril if I have LOW blood pressure?

  • It is advised to avoid this supplement if you have low blood pressure as some of the ingredients may decrease blood pleasure leading to an unsafe drop in blood pressure.

Can I take Noxitril if I have diabetes?

  • Many of the ingredients may lower blood sugar and alter the effects of insulin.

    When adding a new supplement that may lower blood sugar, it is best to monitor your blood sugar daily for the first week.

    If you experience hypoglycemia, stop the supplement and speak with your doctor about possibly altering your regimen.

Are allergic reactions possible with Noxitril?

  • As with all supplements and medications there is the possibility of allergic reactions.

    With this supplement the L-arginine can cause an allergic response or make swelling in the airways worse.

    If you are prone to allergies or asthma use with caution.

Can I take Noxitril with alcohol?

  • As it is best to avoid alcohol when taking supplements, the only known interaction is with the Ginseng.

    Ginseng may increase how fast your body breaks down alcohol.

    Use caution when consuming alcohol.

Can I take Noxitril with Viagra / Cialis?

  • Noxitril may cause a decrease in blood pressure due to the effects of L-arginine.

    This interaction is moderate compared to Hawthorne Berry which is a major interaction.

Can I take if I am taking anti-depressants?

  • Some ingredients in this product may increase nervousness, jitters and possibly induce hypomania in those patients with mental disorders.

    Avoid use of this product if you are taking MAOI’s: phenelzine (Nardil), tranylcypromine (Parnate), and others.

Can I take if I have a bleeding disorder?

  • It is best to avoid this supplement if you are taking blood thinners.

    A few of the ingredients in this product may decrease your body’s clotting ability (thin your blood).

    If you do choose to use this supplement monitor for signs and symptoms in increased bleeding including bruising and bleeding gums.

Can I take with Caffeine or other stimulants?

  • A few of the ingredients in this supplement may stimulate the nervous system.

    Taking in combination with caffeine and other products including pseudoephedrine may increase jitteriness, nervousness, increased heart rate and high blood pressure.

Are there any others medical reasons why I shouldn’t take this supplement?

  • You should stop taking this supplement within two weeks of any surgery.
  • People who have herpes should avoid this supplement as it may aid in the proliferation.
  • If you have Guanidinoacetate methyltransferase deficiency you should avoid this product due to your body’s inability to convert arginine to creatine.
  • If you have kidney problems, it is best to avoid this product as it may increase urine output.

Possible Drug Interactions:


  • Blood Thinners and Antiplatelets
    • NSAIDS
      • ibuprofen
      • naproxen
    • Aspirin
    • Coumadin (warfarin)
    • Plavix (clipidogrel)
  • Nitrates
    • Nitrostat
    • Imdur (isosorbide)
  • Mental Health
    • Lithium
    • Zoloft (sertraline)
    • Lexapro (escitalopram) and other SSRI’s
    • phenelzine (Nardil)
    • tranylcypromine (Parnate)
    • and others
  • Sedatives
    • Clonazepam (Klonopin)
    • lorazepam (Ativan)
    • phenobarbital (Donnatal)
    • zolpidem (Ambien)
    • and others
  • Antidiabetic medications
    • glimepiride (Amaryl)
    • glyburide (DiaBeta, Glynase PresTab, Micronase)
    • insulin
    • pioglitazone (Actos)
    • rosiglitazone (Avandia)
    • chlorpropamide (Diabinese)
    • glipizide (Glucotrol)
    • tolbutamide (Orinase)
    • and others
  • Auto-Immune Medications (immunosuppressants for transplant, rheumatoid arthritis, psoriasis, etc.)
    • azathioprine (Imuran)
    • cyclosporine (Neoral, Sandimmune)
    • mycophenolate (CellCept)
    • tacrolimus (Prograf)
    • sirolimus (Rapamune)
    • prednisone (Deltasone, Orasone)
    • corticosteroids (prednisone, etc)
    • and others
  • Medications metabolized by the liver:
    • Liver Enzyme 2D6
      • amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.
    • Others
      • Theophyline


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Author: Dr. Brian Straub, Pharm.D.

Brian Straub is a medical science liaison and licensed clinical pharmacist. He graduated from the University of Pittsburgh School of Pharmacy in 2011, and is also a registered yoga instructor.

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