Synbiotic 365 Review

Product Reviewed: Synbiotic 365
| 3 OUT OF 5
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Update (10-7-2018): We’re currently in the process of testing Synbiotic 365. Click Here
to see her results so far!

Synbiotic 365 Review Contents

What are Probiotics, Prebiotics, and Synbiotics?
What is Synbiotic 365?
What are the ingredients in Synbiotic 365?
Does Synbiotic 365 work?
Who is Dr. Vincent Pedre?

User Reviews of Synbiotic 365
Frequently Asked Questions

Like a lot of people, I get my news from Yahoo.

The other day I was scrolling through the 400 stories about Trump when I came across this ad…

synbiotic 365 ad on yahoo

I’ve never been a big fan of vegetables to begin with, but it sparked my curiosity.

I clicked on the ad and it took me to a video sales page that looked something like this…

video sales page for synbiotic 365

Yup, it’s a sales video for a product called Synbiotic 365.

Now, I hate these things for a few reasons.

  1.  I’d rather just read an article about something, rather than watch a video on the topic.
  2. Usually videos like this are long-winded and “salesy."
  3. All-too-often they’re click-bait and a HUGE waste of time.

Sales videos like Synbiotic 365 are often just click bait

However, I decided in the interest of my visitors that I would sit through the whole thing.

Here’s what I found…

Gut health.

It’s a BIG problem in today’s society.

And a fella by the name of Dr. Vincent Pedre narrates the epidemic.

You see, turns out a lot of problems start in our gut.

Our “gut flora” plays a key role in keeping us healthy.

In this “internal garden,” we have good bacteria and bad bacteria.

Dr. Pedre says “When the bad bacteria takes over, your gut becomes a war zone."

Synbiotic 365 seeks to restore the gut by adding good bacteria to your gut flora

This doctor, who claims to be New York’s leading gut health authority, blasts certain vegetables (one in particular) for wreaking havoc on our bodies.

He says “odds are you’ve eaten this in the last 5 days." And of course, the discovery will upset us, as it’s nothing short of “shocking." This dramatic build-up goes on for 25 minutes before he actually shares this forbidden vegetable.

Which is…


Dr. Pedre, the maker of Synbiotic 365 claims that corn is bad for gut health

Yup, corn.

Looks tasty to me.

But because corn is doused with endless pesticides, Dr. Pedre says it’s become a “gut disruptor." And the solution?

Synbiotic 365.

Before we dive deeper into Synbiotic 365, let’s talk more about probiotics and their importance to our health.

RELATED: BioX4 Reviews By Nucific – Is It Worth $1000 A Year?

1.  What are Probiotics, Prebiotics, and Synbiotics?

Probiotics, prebiotics, and synbiotics are good for gut health and constipations

Alright, let’s break this down real quick.Here’s what you need to know…

  1.  According to WebMD, Probiotics are “live bacteria and yeasts that are good for you, especially your digestive system." Probiotics are often found naturally in foods (like yogurt) and we can safely take them as supplements. Source
  2. Prebiotics are typically high-fiber foods that are taken to “feed” the probiotics, and they help to maintain the balance of gut bacteria. Source
  3. And finally, Synbiotics are foods or supplements that combine both probiotics and prebiotics in a sort of “synergism." These are taken to “selectively stimulate the growth and by activating the metabolism of one or a limited number of health-promoting bacteria, thus improving host welfare." Source
Your crash course on probiotics, prebiotics and synbiotics

All together, these “biotics” promote overall integrative health.


That’s your crash course in Pro- Pre- and Synbiotics.

2.  What is Synbiotic 365?

Synbiotic 365 was created by the company United Naturals to help restore gut health. 

Synbiotic 365 gut health packaging

The sales video and advertisement link to the company’s website, but there really isn’t much information about the product listed on the site.

Here’s what it does say…

United Naturals Synbiotic 365

Of course, poor gut-health can leave us suffering with a host of symptoms.

But the Synbiotic 365 video really hones in on one symptom in particular: obesity caused by overeating.

It’s the pain-point of SO many Americans.

It’s true… if you can speak to our weight-gain, and convince us you have the solution, then you’re pretty much guaranteed to get rich.

Synbiotic 365 leverages the pain point of obesity and weight loss

So naturally, Synbiotic 365 really focuses on the weight-loss benefits of their product. But does it really work?

And if so, how?

To answer that, let’s have a look at the ingredient profile.

3.  What are the ingredients in Synbiotic 365?

Synbiotic 365 is loaded with vitamins, which is never a bad thing.

But if you wanted a vitamin, you’d go buy a vitamin. You’re here for the biotics.

As for the Probiotic Blend, it contains 30 billion CFU.

Look, I might not be the leading-authority on gut health and probiotics… but I’m a pretty smart guy, so I’ve done the research and here’s what you should know about CFU’s, or “colony forming units."

Probiotics like Synbiotic 365 are measured in CFU, or colony forming unit

Alright, so Synbiotic 365 contains 3 billion of these guys in one serving (1 capsule), which should be more than plenty for your needs.

And the probiotic blend consists of the following good bacteria:

  • Lactobacillus acidophilus
  • Bifidobacterium lactis
  • Lactobacillus paracasei
  • Lactobacillus plantarum
  • Lactobacillus casei
  • Lactobacillus reuteri
  • Lactobacillus salivarius
  • Lactobacillus rhamnosus
  • Streptococcus thermophilus
  • Bifidobacterium bifidum
  • Bifidobacterium longum
  • Saccharomyces boulardii

See below for the full ingredient list for Synbiotic 365

Synbiotic 365 ingredient list

4.  Does Synbiotic 365 work?

And now… the moment of truth.

Does this supplement work to radically improve your mood, aide in digestion, help you to get better sleep, melt away those unwanted pounds, AND deliver on the handful of other benefits it promises?

The short answer is “Maybe."

Does Synbiotic 365 work for better gut health?

Hear me out…

First off, according to one study, “Probiotics, prebiotics and synbiotics have systemic effects on the host’s health metabolism and immune system." Source

OK, that’s a good start, but what kind of “systemic effects” do they have?

Well, they’ve been found to help with many maladies, including diarrhea, constipation, inflammation, and have even been shown to alleviate symptoms of allergy, cancer, AIDS, and respiratory and urinary tract infections. Source

There are many benefits of probiotics like synbiotic 365

Seems legit.

But what about reversing the effects of obesity and aiding in weight loss?

According to the study above…

“A breakthrough paper published in Nature reported that microbial population present in the gut is different for obese and lean people, and that when obese people lost weight their microflora resembled to that of lean people.

Diets containing high fibers typically have lower degrees of fat and energy density, and helpful for reducing the risk of obesity by promoting satiety and weight loss."

Probiotics and synbiotics were studied and published in Nature journal

So it’s true that “the introduction of probiotics, prebiotics, or synbiotics into the human diet is favourable for the intestinal microbiota." And thus it may help with obesity, along with a number of other conditions.

We can also include on the long list of benefits the potential to “treat irritable bowel syndrome, enteritis, bacterial infections, various gastrointestinal disorders and diarrhoeas… and lactose intolerance." Source

Finally, one study is even looking at evidence for the use of supplementation with probiotics, prebiotics, or synbiotics “for the prevention and treatment of dermatological diseases in adults." Source

Some researchers are studying whether or not probiotics, like Synbiotic 365, can help with skin conditions

Phew! That’s a good handful of scientifically-backed reasons to start using probiotics.

Like yesterday.

However, with all that said…

Synbiotic 365 contains many of the same ingredients as other products sold on the market.

There’s really nothing special about it.

So if you do notice positive results by taking this supplement, you’d likely get the same results by using other synbiotics.

RELATED: Peptiva Review

5.  Who is Dr. Vincent Pedre?

Dr. Vincent Pedre is the brains behind Synbiotic 365.

Dr. Vincent Pedre is the creator of Synbiotic 365

A graduate of Cornell, Dr. Pedre is New York’s self-proclaimed leading authority on all things gut health. He’s the resident Doctor at United Naturals, and also runs Pedre Integrative Health in NY.

He was even featured on CBS…

He’s written books on gut health and the GTI, including “Happy Gut."

So from what I can tell, Dr. Vincent Pedre is the real deal when it comes to learning how to restore your gut health.

6.  User reviews of Synbiotic 365

Reading through user reviews can tell us A LOT about the efficacy of a product, and what to experience while taking it.

Reviews also help to take the edge off the purchase.

Positive reviews = street cred.

Negative reviews = steer clear.

But what happens when there are NO reviews at all?

Synbiotic 365 does not have any user reviews yet

Well, it should cause us to stop and ask some questions.

Is the product brand new? Has anyone even tried it yet? Why isn’t it sold on Amazon?

Was it so bad (or so good!) that people don’t even bother reviewing it?

In my experience, the more positive reviews a product has, the more we can trust it.

With that said, I searched high and low for user reviews of Synbiotic 365, and I came up bone dry.

So if you decide to try this product, just know that it might not be super effective.

Our Personal Test Results

We sent a free box of Synbiotic 365 to one of our site visitors via our STEPuP program.

synbiotic 365 reviews - kathleen

Her name is Kathleen, and she’s been using it for the last 10 days.

Here are her thoughts so far:

9/28/18 – Day 1

As a result of being prescribed 5 days of Prednisone combined with a prescription for antibiotics (for a sore throat), I developed a yeast infection in my mouth.  I was then prescribed Nystatin to combat the thrush.

After 28 days on Nystatin the yeast is still there.

It seemed to get a little better while taking the Nystatin, but when I stopped taking the Nystatin it came back.  So, I decided to see if Synbiotic 365 would help with this condition.

Today is my first day of taking this product and so far, I don’t see any difference, but I think it’s too early to tell yet.

Day 2:  No noticeable difference regarding my thrush condition or otherwise.

Day 3:  Again no noticeable difference in any way.

Day 4:  No noticeable difference with the thrush.  As a side note, I do seem to be having more bowel movements than I normally do.

Day 5:  Still no noticeable change regarding the thrush.

Day 6:    Same as day 5.

Day 7:  It seems like that thrush condition might be beginning to lessen slightly.

I don’t notice quite as much of a cotton-like feeling on my tongue and there doesn’t seems to be as much of it on my tongue.  More of a spotty look than a solid covering.

I am not currently taking any other course of action so that I can measure the effectiveness of this product for this condition, except that I do try and stay away from sugar so as not to feed the yeast.

Day 8:  Same as yesterday.

Day 9:  Same as day 7.

Day 10:  I can still see areas of yeast overgrowth on my tongue, especially in the morning, but it does seem to be less noticeable than when I started, especially in terms of that horrible cotton like feel that thrush gives you.

Day 11:  Nothing has changed since yesterday.  I still notice areas of yeast on my tongue.

Day 12:  Same as day 11

Day 13:  Not better or worse for the past several days.

Day 14:  Unfortunately I am not noticing any further improvement in my condition.  I am thinking that this may be effective for some other issues but not really for thrush.  I seem to be in a holding pattern where my symptoms are not getting worse, but they are not really getting any better either.

Day 15:  I forgot to take the probiotic today, but things seem the same as it has been for about the past week.

Day 16:  Still no change

Day 17:  Still no change either way.  It seemed to get better up to a point and then stop – but it hasn’t gotten worse.  This product may be better used for maintenance rather than cure.

Synbiotic 365 FAQ’s

7.  Is it safe to take?

Synbiotic 365 is safe to use

This supplement is safe to take, as it contains mostly vitamins and “good” gut bacteria.

We’ll discuss this more in the “Side Effects” section, but generally speaking, users of probiotics, prebiotics, and synbiotics do not experience any unwanted effects.

8.  Where can I buy it?

As far as I know, you can only purchase the supplement from the official United Naturals website.

You can buy Synbiotic 365 from United Naturals website

This isn’t really cause for concern, as many companies like the control of only selling their products through their own website.

9.  How much is it?

Synbiotic 365 costs $45 per box.And I believe each box comes with 30 capsules.

And the more boxes you buy, the more you save.

Synbiotic 365 price

As far as probiotics go, this price is pretty standard.

10.  Is there a guarantee?

Yes, the company offers a 30-day money-back guarantee on the gut health supplement.

Synbiotic 365 comes with a 30-day guarantee

11.  What are Prebiotics side effects?

Generally speaking, you shouldn’t notice side effects from taking this type of supplement.

However, one study claims that some prebiotics side effects include bloating and gaseousness, and abdominal pain and diarrhea with larger doses. Source

12.  Do probiotics make you poop?

Synbiotic 365 is a probiotic that might help you poop and alleviate constipation

Yes, probiotics make you poop.

Well, they help your good gut bacteria to survive and thrive, which helps to regulate bowel movements.

If you’re looking for the best probiotic for constipation, I can’t say for sure this is the one, but you might give it a try.

13.  Does this probiotic help with yeast infections?

Probiotics may help with yeast infections, but the jury is still out

While some women claim that probiotics help with yeast infections, the jury is still out whether or not probiotics, prebiotics, or synbiotics help to alleviate the symptoms of this type of infection.

Synbiotic 365 probably does not help yeast infections.

14.  Recommendations

There is nothing special about this supplement that makes me want to recommend it to my visitors.

In fact, I would sooner recommend a different gut health supplement: ActivatedYou Probiotic.

I’d also suggest reading this review on Probiotics Pills Sold in Stores (GNC, Walmart, Walgreens, CVS, and more)

Synbiotic 365 is hyped-up by a marketing video that takes 30 minutes to get to the point.

The ingredients are nothing to write home about, and there are no user reviews that help to earn our trust in the product.

Synbiotic 365 is largely marketing hype.

Sure, Dr. Vincent Pedre seems like a qualified dude to create and market a gut-health probiotic.

But other than that, there’s nothing all that attractive about the offer.

So I would recommend against this product, at least until we learn more about it and hear from real people who’ve tested the product over time.

If you’re interested in testing out this supplement free of charge, click here now!

Have you tried Synbiotic 365?

If so, write your review in the comments below!

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Author: Rob Miller

Rob Miller founded over 7 years ago, and has been the chief editor ever since. He has a diploma in Advanced Dietary Supplements Advisor, and worked at GNC for 3 years. He KNOWS supplements, both inside and out. Rob currently resides in Jupiter, FL, with his wife of 4 years.  Learn more about him in his Bio here. Follow him on Twitter , Facebook, LinkedIn, or find him on Google +.