Zantrex 3 Review – Does The Blue Bottle Work?

By: Rob Miller
31 User Reviews
Fact Checked On: 8-7-2018


Home » Weight Loss Supplements » Zantrex 3 Review – Does The Blue Bottle Work?

Like so many Americans, I want to lose weight.

After all, who doesn’t want that slimmed down body that walks tall with confidence?

But here’s the thing. . .

I don’t really want to exercise or eat healthy, I just want to take a magic pill that just sheds the weight away.

Is that too much to ask?

Sound familiar? The truth is, we live super busy lives.

And it can be hard to find the time and energy to exercise consistently.

And sticking to a healthy diet often seems like an impossible task in itself.

So why can’t we just pop a little pill, sit back and relax, and watch those unwanted pounds vanish into thin air?

Of course we all know this is not possible, right?

I mean, it just sounds way too good to be true.

But hey, we can dream can’t we?

Well, maybe it IS possible with the help of a fast-acting, weight loss pill called Zantrex 3.

zantrex 3 blue bottle

When I first came across Zantrex 3 in Walgreen’s, I was a bit skeptical.

zantrex 3 at walgreens

I studied that blue bottle closely.

I read all of the ingredients and potential side effects.

It seemed to check out fine.

But what really sealed the deal is that it actually claims you can lose weight without lifting a finger, let alone running on a treadmill for hours.

So how could I not want to at least take this supplement for a test drive?

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At this point, you’re probably thinking there is a catch, but believe it or not, there isn’t.

In fact, Zantrex 3 actually conducted a thorough clinical study on their product to show its effectiveness at burning fat without having to exercise or diet.

What is Zantrex 3 Blue Bottle?

Marketed as a rapid weight loss formula, Zantrex 3 promises to deliver an extreme amount of energy and also to help you finally lose those unwanted pounds.

In fact, the tagline on the Zantrex 3 website says it all:

“Because the weight won’t lose itself.”

Clever, eh?

The product description goes on to say:

“Zantrex-3 is way beyond ephedrine, way beyond fat burners, way beyond everything on the market today.”

According to a study published on their official site and on the label, Zantrex 3 users saw an average weight loss of 546% more than “America’s #1 selling ephedra based pill.”

Unfortunately, the makers of Zantrex 3 don’t actually state what that #1 selling pill actually is.

Also, if you look at the details of the study that was conducted in 2007, you’ll see that no results have been posted. content/uploads/2011/12/no results

With that said, however, they do give you details about the study on the products own label.

zantrex 3 vs hydroxycut and lipozene

And they DO mention which products it was compared to…

Lipozene and Hydroxycut, which are actually 2 weight loss pills we’ve reviewed.

If this study is legit, that’s 546% more weight loss than you’d experience taking the best-selling pill on the market!

That’s reason enough to stop whatever you’re doing and take the time to learn more about this weight loss pill.

At least that was my thinking.

See our Comparison Between Zantrex 3 Blue Bottle Vs. Red Bottle

zantrex red vs blue bottlesWhile Zantrex 3 does a good job of selling and marketing their product, it hasn’t come without a price.

Doctors have weighed in on the potential dangers and side effects from taking a supplement such as Zantrex 3, which is not subject to FDA scrutiny (similar to all other OTC supplements).

They caution that taking a product like this may have hidden consequences which could be detrimental to your health, even frowning on reality TV star “Snooki’s” endorsement of it.

zantrex 3 snooki

But of course they’re going to say that, they’re doctors for crying out loud!

And just like with taking any supplement, you want to use your common sense, read the reviews and fine print, and proceed with caution.

You shouldn’t automatically count out any product simply because it sounds too good to be true.

Instead, do your due-diligence and make an informed decision on whether or not you’ll try the supplement.

Which brings us to the bottom line.

Does Zantrex 3 really work?

Can the blue bottle really deliver on its promises?

And if you take it, will you be included among those who experienced rapid weight loss without having to exercise or go on a diet?

We set out to find answers to these questions.

Like always, we read through several other weight loss review sites, and we poured through discussions and forums to get a good sense of Zantrex 3 users’ results and their experiences before we decided to take a crack at it.

And here’s what I found. . .

Zantrex 3 Side Effects

The majority of users that I came across in forums and on review sites were seeing some small side effects from Zantrex 3, most notably headache, trouble sleeping, and flushed skin.

does zantrex 3 cause headaches

So what’s causing this?

My guess as to what’s causing most of these side effects would be because the supplement contains the stimulants caffeine and yerba mate.

Both of these ingredients have been known to cause mild headaches and sleep disturbance in users.

yerba mate headaches

caffeine causes headaches

The reason being is that stimulants such as these affect the central nervous system.

I would imagine staying hydrated throughout the day would help in part to alleviate these side effects.

The users who experienced flushing of the skin are likely sensitive to niacin (nicotinic acid).

But the makers of the supplement say those who experience some flushing of the skin are not to worry, as it is typically mild and transient.

Other potential side effects listed on the Zantrex 3 site might include:

  • Nervousness
  • Irritability
  • Rapid heartbeat

Zantrex 3 Reviews

Finding reviews of the Zantrex 3 Blue Bottle was relatively easy.

The first thing I searched for was before and after photos.

When you search google, you’ll see a few of them, most notably this one:

Zantrex 3 before and after.
Zantrex 3 before and after.

Image by

However, whenever I see a before and after picture, I’m always a bit skeptical.

In this case, it turns out it was for good reason.

Case in point, run an image search for this particular picture.

search google for before and after pictures

When you do, you’re presented with about 5 pages that contain matching images.

If you click on the first result, you’ll see the before and after picture towards the middle of the page. content/uploads/2011/12/fat burner

HOWEVER, if you click on the result 2 down from there, you’ll see that this before and after photo was taken by Mens Journal!

mens journal before and after

This article in Mens Journal outlines how Charlie went through an 8 week “transformassacre”, in which he lost a ton of weight.

Essentially, one website stole from the other.

fake zantrex 3 before and after pictures

How about Youtube Vids?

Normally Youtube is ripe with crappy videos that call themselves “reviews”, but end up turning out to be nothing more than advertisements for the product.

This is not the case with Zantrex 3.

For example, you’ll find this video review when you do a search on Youtube.

Throughout the video, she details how she takes it, why she does NOT take it late in the day, and her ultimate results.

She mentions in the comments section below the video that she lost 81 lbs. from taking Zantrex 3, which is pretty impressive.

zantrex 3 review on youtube

Some of the youtube videos, however, aren’t so informative.

Take this one for instance:

She doesn’t really mention any results from taking Zantrex 3, but does say that she will post a follow up.

That was 5 years ago, and from what I’m seeing it’s her one and only video on the subject. content/uploads/2011/12/no other

Reviews on Amazon

Since Zantrex is also sold on Amazon, there are a wide array of reviews about the product.

Reviews are fairly mixed, with about 47% of them rating it 4 stars or better, and 40% rating it 2 stars or less.

average star rating for zantrex 3 on amazon

Again, one of the most prevalent statements we hear explicitly mention the side effects from taking Zantrex 3.

As one 5-star review said of the product:

“I use these early in the day with my first meal, if I take one independently from food then I get a little nauseous and the niacin flush feels horrible.

I only use one and usually no more than one a day they seem to help maintain and I possibly feel a little more energy that is why I take it with my first meal of the day.

If you take it later or in evening I believe it affects my ability to fall asleep.”

One recurring theme from the positive reviews is the sheer amount of energy that it produces.

Almost every other review mentions something about how well it works to give you more energy, as noted by the screenshots below:

zantrex for energy content/uploads/2011/12/energy content/uploads/2011/12/energy

One guy even said it works great as a pre workout supplement.

zantrex as a pre workout

The negative reviews, on the other hand, don’t paint a very rosy picture.

Most of them simply say that Zantrex 3 doesn’t work.

negative reviews of zantrex

One thing I also noticed was that the vast majority of reviews were written by women, which suggests that it’s specifically supposed to help women lose weight.

Related Article: Best Female Fat Burners

Ingredients in Zantrex 3

Zantrex 3 Blue bottle works through a combination of proprietary ingredients, divided into 2 categories: weight loss and energy.

The result is. . . you guessed it, a powerful one-two punch.

The ingredients you should be concerned with for weight loss include:

  • Yerba Mate
  • Guarana
  • Damiana

The ingredients listed for energy are:

  • Trimethylxanthine (fancy word for caffeine)
  • Guarana Extract

In total, there are about 24 other ingredients listed in Zantrex 3, but the ones listed above are the primary ingredients used.

Here’s a snapshot of the label:

zantrex 3 blue bottle label

The full ingredient list includes:

  • Green Tea Extract
  • Kola
  • Schizonepeta
  • Black Pepper Extract
  • Rhodiola Crenulata
  • Asian Ginseng
  • Maca Root
  • Cacao Seed
  • Black Tea Extract

There are still other ingredients listed on the bottle, but these are mainly fillers and/or additives for coloring and to keep the product fresh.

The ingredient Trimethylxanthine, also commonly called xanthine, is especially important to consider.

The Zantrex 3 site says the product contains “a significantly potent xanthine (i.e., caffeine and caffeine-like stimulants) mixture of about 300 mg per serving.”

To put this in perspective, the typical 8-oz cup of coffee contains about 95 mg of caffeine.

how much caffeine in coffee google search result

So go slow, and remember, there’s no harm in taking less than the full recommended dose.

If you get the caffeine-induced jitters and heart palpitations, then you should definitely consider taking less than the full dose, or staying away from Zantrex 3 altogether.

One other option might be to combing it with L-Theanine.

The combo of L theanine and caffeine has been show to not only help with weight loss, but also with cognitive performance and mood. content/uploads/2015/04/dr l

At the end of the day, you know your body best, so use your best judgement and consider testing the waters before diving in head first.

Zantrex 3 Warnings

Also, with this in mind, the makers of Zantrex 3 offer up a word of caution.

That is, you’ll want to consult with your physician before using it, especially if:

  • You’re taking meds
  • You are sensitive to certain stimulants
  • You have an underlying medical condition

And of course, steer clear of the product if you’re pregnant or nursing.

You’ll also want to limit other caffeine-like stimulants — whether they be food, drinks, or supplements — while taking Zantrex 3.

What to expect when Taking Zantrex 3

Within only a few short minutes after taking Zantrex 3, you’ll begin to feel it kick in.

You’ll likely experience a boost in energy and motivation, which tends to level out over time.

They say if you take it before a eating a meal, you might experience a loss of appetite.

But this tends to go away after you’ve used the pill for a while.

Within a few weeks of taking Zantrex 3 you should notice dramatic results in the weight loss department, especially if you’re exercising and eating well.

In fact, one reviewer emphatically said, “They work! Just take one NOT two as directed. I lost about 15-20 effortlessly.

They definitely cut my appetite and gave me energy.”

Review on weight loss supplement Zantrex 3
Review on weight loss supplement Zantrex 3

My Results From Taking Zantrex 3

I’m not really a big guy to begin with, but I could definitely stand to lose about 15 pounds.

I’m already active, but my diet sucks, so I needed to stay off of the pizza and beer for a few days to not skew the results.

I know, it’s rough, but I went ahead and took one for the team.

The dosage instructions on the Zantrex 3 blue bottle say to take 2 capsules, but I always like to start off with just one or 1/2 the dose to see how my body responds, and then adjust accordingly.

how to take zantrex 3 blue bottle

It’s a good thing I did that, because after about an hour I began to feel the same side effects that were mentioned from the other users of Zantrex 3.

I think for me though, the side effects began to wear off quickly, because I didn’t experience them for more than an hour or so.

And here are the positive effects: I felt a tremendous surge of energy, almost as though I could run a 5k with no problem at all.

Exercise and eat healthy while taking weight loss supplement Zantrex 3
Exercise and eat healthy while taking weight loss supplement Zantrex 3

After taking the Zantrex 3 blue bottle for about a week, I noticed that I dropped about 5 pounds, and the side effects were non-existent.

Remember, I wasn’t a big guy to begin with, so shedding 5 pounds in one week isn’t all that bad.

Over time, I think that the effectiveness starts to wear off.

But regardless, Zantrex 3 definitely works to give you that kick-in-the-butt to get you motivated to exercise and workout.

So in that respect, it fulfilled its promises just fine.


The good news is that Zantrex 3 is cheap enough to give it a shot without having to worry that it will break the bank.

In fact, I picked up the blue bottle for just $20 at Walmart, and found that it’s actually one of the cheapest weight loss pills you can buy there.

When compared to some of the other ephedra-based fat burners I have tried, I think it works better than most.

It seems like most of the people that did not experience good results from taking Zantrex 3 did not combine it with any diet and exercise, which is obviously crucial to anyone who is looking to lose weight and keep it off over the long term.

Pro tip

This reminds me, while supplements and fat-burners like Zantrex 3 can be powerful and fast-acting on their own, it’s important to keep in mind your overall lifestyle.Even on their website, they write “Use in conjunction with any sensible diet and exercise program.”

And it’s true, while you might lose 5, 10, or 15 pounds using a weight loss pill, imagine the weight you could lose if you worked out and stuck to a healthy diet while simultaneously taking a pill!

Now we’re talking serious weight loss!

If you’ve tried Zantrex 3 and were happy with the results, the makers of the supplement also came out with a different formula which is supposed to be more potent than the original blue bottle, check out our review of that one here.

Have You Used Zantrex 3 Too?

Leave Your Review Below!

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User Reviews

Have you used this supplement?

By Casey,  May 24, 2013

So about 2 days ago I started taking the blue bottle I currently and 5'4 and weigh about 170 I used to weigh 135 and would love to get back there. I gained the freshman 15 and then some.


I did a lot of research on this am here are some things I have learned. The red bottles have ephedrine in it and the blue don't.


The FDA doesn't approve weight loss pills with that in there. So if your taking the red ones just be careful.


Also the red ones are for people who athletes or work out a lot so if you are taking the red and just sit down on the couch or at a desk all day the red ones arnt for you. I am an athlete but I don't want to put the ephedrine in my body so I have taken the blue ones.


I haven't really had any side effects and here's why. I drink a lot of water when I take it and I make sure I dont immediately sit on my butt after I go for a little walk or go to the gym.


These pills are supposed to give you energy to do stuff and move around, so move a little. The people that see the best results are the ones who move around even a walk or something small.


The pills have made me more hungry but that is because it increases metabolism. So to curve that I drink more water and i have noticed i have been eating smaller portions because i get fuller feelings sooner.


In 2 days I have lost 2 pounds. And so my recommendations are
1. Don't take the red unless you are active (I am an athlete and I don't even take them)
2. If you take them drink plenty of water (makes sure you won't feel dizzy)
3. Move! (Right after you take the pills don't just sit down move around a little it'll keep you from feeling nauseous)
4. The burning feeling will subside, make sure you drink plenty if fluids!)
5. Avoid sugary things!


Candy! Any thing that is supposed to help you lose weight doesn't work well with sugar and fats.


Always consult a doctor especially if you are taking other medicines or on other weight lose pills (that's dangerous!)

Ill keep you updated on my progress good luck all!

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66 out of 69 people found this review helpful.

By Jennifer,  Jan 30, 2013

I took the blue bottle and had very good results even though I did not take them as recommended. The most I ever took was 3 a day but still lost about 60 lbs over a couple months.


I did experience the side effects but only initially til my body adjusted to taking them. The did lose their effectiveness after a while though.


I did not regain the weight after taking them either. I have tried several others with no results.


I am planning on beginning them again now that I have been off of them for a while.. I also tried the red bottle for about a month but did not like them at all.


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43 out of 45 people found this review helpful.

By tee,  Jul 16, 2013

I started 4 days ago at 220 today I'm 209 ! Idk how its possible lol but I love the results ....btw idk if its just me but it made me poop and urine alottttt..


I guess thats where the weight loss came from lol !!!!

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33 out of 37 people found this review helpful.

By Danielle,  May 20, 2013

I just started the blue bottle yesterday today is my second day and I feel great. I have completely changed my eating habits so sugars, junk food, extra calories.


I did feel the energy yesterday which was great and I also did cardio for about an hour. I have never felt this good.


I will keep you posted!

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29 out of 32 people found this review helpful.

By Tim,  Aug 13, 2013

Hi, I've been taking the red bottle for about a month. At first it gave me really bad side effects for a week and now it's fine.


I haven't seen any results but it does give me energy, which I love. Today I purchased the blue bottle and I won't be using the red one anymore since everyone says blue works better.


How long should I wait to switch over to blue? Will it be ok if I start using it tomorrow?


I took one red one early this morning.

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13 out of 16 people found this review helpful.

Rob Miller: Hey Tim,
It shouldn’t be a problem to switch the next day, but I would advise you to err on the side of safety, and wait 2 or 3 days before taking the Blue.


Ask A Question

User Questions and Answers

za ntrex-3 blue bottle what is the prescribed dose and cautions -Charles

The instructions on the bottle read: For weight loss, take 2 capsules with a full glass of water 15 minutes before main meals. For a significant energy boost, take 1 or 2 capsules as needed. Do not exceed 6 capsules in any 24-hour period. Use in conjunction with any sensible diet and exercise program. Individual results will vary. Then Warning states: Do not take Zantrex-3 Fat Burner (red bottle) and Zantrex-3 (blue bottle) at the same time. Do not substitute one product for the other. This product contains a significantly potent xanthine (i.e., caffeine and caffeine-like stimulants) mixture, of about 300 mg per serving. Consult your physician before use if you are taking medication, sensitive to stimulants, or have a medical condition. Do not exceed suggested daily serving. Not for use by individuals under the age of 18 years. Do not use if pregnant or nursing. People sensitive to Niacin (Nicotinic Acid) may experience flushing of the skin that is generally mild and transient. Use only as directed. Keep out of reach of children.- Rob

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6 out of 6 people found this question helpful.

I have been taking the blue bottle for 2 days now and can't sleep at night and I am feeling nausea. Do u recommend I continue taking them? -Elizabeth

It sounds like you're having a bad reaction to the supplement. I recommend you discontinue use.- Rob

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6 out of 6 people found this question helpful.

Regarding the blue bottle, can I take them without food and if so will I see the same results? -Tiffany harig

I would just take it as directed.  The label says you should take 2 capsules with a full glass of water 15 min. before main meals.- Rob

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5 out of 5 people found this question helpful.

I work nights and just started with the red bottle how long before it wears off so i can get rest? -Mela

Everybody's different, but it's not recommended that you take it within 6 or so hours before you're planning on going to bed.- Rob

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4 out of 4 people found this question helpful.

Author: Rob Miller

Supplement Critique

Rob Miller founded over 7 years ago, and has been the chief editor ever since. He has a diploma in Advanced Dietary Supplements Advisor, and worked at GNC for 3 years. He KNOWS supplements, both inside and out. Rob currently resides in Jupiter, FL, with his wife of 4 years.  Learn more about him in his Bio here. Follow him on Twitter , Facebook, LinkedIn, or find him on Google +.