Membrane Integrity Factor Review

By: Rob Miller
MD Reviewed By: Helen Okoye, MD What's This?
Fact Checked On: 3-20-2020

Membrane Integrity Factor Overview

Getting old is the pits.

Wrinkles, joint pain, apathy, saggy boobs, a failing sense of direction.

And there’s really no getting around it.

…Or is there?

When a company comes out and says they’ve found “a scientific breakthrough to anti-aging,” well, we can’t help but hear them out. Because what if?

What if they caught lightening in a bottle, so to speak, and somehow stumbled upon the perfect formula to stop aging?

Despite what Membrane Integrity Factor says, here is no such thing as the fountain of youth, so head for the fountain of bacon

(Fountain of youth jokes never get old.

See what I did there? 😉

Alright, so I’m just gonna burst the bubble right here and now.

There is no such thing as a fountain of youth, anti-aging product that truly works to stop the process of growing old.

But you knew that.

Reversing or off-setting the effects that time and aging has on our bodies is of course not possible, and while certain aspects of the process are undesirable, who would really want to turn the clock back if given the chance?

While some creams, lotions, pills and serums may help to tighten the skin, reduce the wrinkles, and even alleviate pain, you will never stop aging.


BUT… can we slow down the aging process?

Recently I came across an ad on Yahoo for a product called Membrane Integrity Factor.

I came across this Membrane Integrity Factor ad while searching the internet

They offer up some pretty crazy claims, like this one…

“Aging used to be thought of as an inevitable process.

Now doctors and scientists alike think of aging as something that can be slowed down and sometimes reversed.”

Hmmm. Seems a little fishy.

So I had to dig in to Membrane Integrity Factor to learn what it’s all about.

Could it really have properties that slow and reverse aging?

If not, is it at least good for us in some way?

In this review I answer all of your burning questions about this supposed scientific breakthrough product.

What is Membrane Integrity Factor?

membrane integrity factor review

Well… it’s a pill.

And it has two main ingredients: 2AEP and HGHR.

We’ll cover these in the next section, but right now I want to briefly discuss the so-called brains behind the product, and what Membrane Integrity Factor claims it will do for you.

So it (allegedly) all started with a German doctor named Hans Alfred Nieper.

Dr Nieper is supposedly the inventor of Membrane Integrity Factor

Who is Dr. Nieper?

The fine folks at Membrane Integrity Factor have a WHOLE page dedicated to the now-deceased doctor.

Doctor Nieper has no affiliation with Membrane Integrity Factor

So you would think that this Dr. Nieper was the guy who created the product…


Or at least a leading scientist behind the formula…


Or is somehow — in some way — affiliated with Membrane Integrity Factor.

Dr. Nieper is not affiliated with Membrane Integrity Factor in any way

The makers of the product picked some random doctor from Germany (who died last century) to be their front-man and the product’s inventor.

By now, red flags are probably raised in anyone that cares about the integrity of the things that they decide to put in their body.

They literally wrote on the box: “Formulated by Hans A. Nieper, MD.

The makers of Membrane Integrity Factor falsely claim that Dr. Nieper formulated the product

You can’t do that.

But jokes on them because I’m gonna systematically dismantle their every bogus claim so we can get to the truth of the matter.

Here are some of the claims that the makers of the product essentially shovel at the reader.

Membrane Integrity Factor big bold claims

According to the website, “Membrane Integrity Factor® delivers essential nutrients to our outer cell walls using a patented ‘Mineral Carrier’ to seal and protect them (Which Prevents Aging).”

So what is this magic ingredient that prevents aging? And how exactly does it work?

Let’s have a look at the ingredients.

What are the Membrane Integrity Factor ingredients?

To understand the Membrane Integrity Factor, we have to first get acquainted with Calcium 2-aminoethylphosphate (2-AEP), and to a lesser extent, HGHR.

2-AEP– This “vital component in the structure of cell membranes… has beenshown to help maintain cell membrane integrity and improve cellular functions.” (Source)

2-AEP is the main ingredient in Membrane Integrity Factor anti-aging pills

2-AEP was actually discovered by Erwin Chargaff in the early 1940’s, and it was later patented by Hans Alfred Nieper and Franz Kohler.

It’s essentially a mineral transporter, which functions like so…

“[2-AEP] goes into the outer layer of the outer cell membrane where it releases its associated mineral and is itself metabolized with the structure of the cell membrane.

The effect here is an increase of the electrical condenser function of cell membranes to resist toxins and viruses which may otherwise enter the cell and cause cellular degeneration.” (Source)

Membrane Integrity Factor supposedly works at the cellular level

And according to Nutrition Review, 2-AEP has been shown to support everything from multiple sclerosis to diabetes, to asthma and immune disorders. (Source)

The makers of Membrane Integrity Factor don’t disclose how much of the ingredient is contained in the pills.

On to our next ingredient… HGHR.

hgh myths vs facts

The Human Growth Hormone Receptor, or HGH, is what regulates things like muscle and bone growth, metabolism, and possibly heart function (Source).

Unfortunately, this critical hormone naturally declines as we get older.

The Human Growth Hormone, or HGH, is an ingredient in Membrane Integrity Factor

According to WebMD, some use HGH much like anabolic steroids — “in an attempt to build muscle and improve athletic performance.

Yet HGH’s effect on athletic performance is unknown.” (Source)

Dang right it’s unknown.

In fact, Harvard did a study on the efficacy of HGH for building muscle composition and athletic performance, and they claim it isn’t shown to have any effect whatsoever (Source).

So if it can’t really help people in the here and now, how can it slow the effects of aging and make you live longer into the future?

Membrane Integrity Factor claims it can slow the effects of aging, but the ingredients don't back it up

Who are we to believe?

Membrane Integrity Factor, or WebMD and Harvard?


How I know Membrane Integrity Factor is Bogus

Anytime a company boldly claims that they’ve discovered the fountain of youth, you just have to be skeptical.

As for Membrane Integrity Factor, there is no research to back up their promises.

While the ingredients 2-AEP and HGH might help to protect you from toxins and rejuvenate your cells, there is no way they can slow the effects of aging, let alone reverse the effects altogether.

Membrane Integrity Factor reverse aging pills

And it’s sad, because there are countless shady companies like this one just taking people’s hard-earned money left and right.

But a little up-front research goes a long way.

In fact…

WebMD came out with a brilliant article on how to spot anti-aging scams.

WebMD wrote a great article on how to spot anti-aging scams like Membrane Integrity Factor

The article details the 15 warning signs to look out for.

I wasn’t surprised to learn that Membrane Integrity Factor checks off just about every box, including…

#3 –Usage of phrases such as “scientific breakthrough,” “exclusive product,” “secret ingredient,” or “active remedy.”

#6 – Attempts to convey credibility, such as wearing white lab coats and stethoscopes, posing with microscopes, claiming to be a medical doctor or referring to “academies” and “institutes.”

#7 – Not mentioning potential side effects and making claims that sound too good to be true.

anti-aging with Membrane Integrity Factor pills

#8 – Using simplistic rationales; anti-aging quacks claim that that the answer is as simple as manipulating a single hormone.

#12 – Telling misleading interpretations of studies or outright lies about effectiveness.

And the list goes on.

Look, you just can’t turn back the biological clock.

There is no such thing.

You cannot turn back the biological clock and get younger with the so-called anti-aging pills Membrane Integrity Factor

Membrane Integrity Factor Reviews

The product gets a pretty decent 3.9 stars on

However, things aren’t always as they seem.

I ran the Amazon listing through my fake-review-spotter tool and found that “Unnatural reviews are possible.”

Membrane Integrity Factor potentially has fake reviews

And with only 6 reviews total, I don’t believe they can be trusted.

Especially this one…

Fake review of Membrane Integrity Factor

That just screams F.A.K.E.

But I did come across this next membrane integrity factor review that could be real.

He (or she) goes into detail about his sister using the product (which is weird), but then talks about his own experience using it.

He noticed an increase in energy while taking it… but doesn’t mention if he got any younger. 😉

A positive review for Membrane Integrity Factor

The reason it might be a real review is because he complains about the price and how it took 6+ months to start kicking in.

Finally, the product’s website has a full page of testimonials, but they are all 100% glowing, of course.

Membrane Integrity Factor FAQ’s

Anafuse FAQ's

Who makes Membrane Integrity Factor?

That’s a great question.

On the official website’s ‘Contact’ page, they list a physical address in Oxnard, CA. But unfortunately, the “makers” of the product would rather remain anonymous.

Hmmm, wonder why.

But after a little investigative work, I was able to find the company behind membrane integrity factor.

Deep in their FAQ page, they say that customers can expect to see a charge from “Healthy Techniques” on their credit card statement.

So I looked ’em up.

Healthy Techniques is the maker of Membrane Integrity Factor

Nothing really to report here.

Just a low-budget website with a few products ranging from fat burners, to male sex enhancers, and even some gut health pills.

How do I use Membrane Integrity Factor?

They don’t say how to take the pills.

I imagine you take one pill in the morning with a meal. But I could be wrong.

I’m sure the instructions are on the label.

Are there any side effects with Membrane Integrity Factor?

Adderall comes with it's own side effects, like headache and nervousness

There’s really no telling.

The company isn’t completely transparent about how much of which ingredients the pills contain.

But I do know that HGH is known to cause some side effects.

According to one study, “HGH recipients experienced a high rate of side effects, including fluid retention, joint pain, breast enlargement, and carpal tunnel syndrome.” (Source)

Is it safe to take?dangerous weight loss pills

Again, the company that makes membrane integrity factor doesn’t share the full ingredient profile.

This means we don’t know exactly what’s in the stuff.

Although it’s probably perfectly safe to take, I can’t say for certain one way or the other.

And that’s just the thing with these types of “scientific breakthrough” offers. They purposefully hide the ingredients. Why?

Because if people like me knew exactly what was in them, we could go point-by-point on just how ineffective the product is.

There’s a simple lesson to be learned… if they don’t list ingredients, you don’t buy.

Is it really anti-aging?

Is Membrane Integrity Factor really anti-aging?

No, despite the claims that Membrane Integrity Factor can “slow the aging process,” and sometimes “reverse it”… that’s just not reality.

The formula doesn’t contain anything that can achieve this.

Best-case-scenario from taking these so-called “anti-aging” pills is that your energy improves and maybe you begin to feel younger.

But don’t count on it.

Is it a scam?

Is Pharmacy RX One a scam?

Yes, I believe it is a scam.

Remember that WebMD article about how to spot an anti-aging scam?

Well, Membrane Integrity Factor didn’t exactly pass the test.

In fact, they failed miserably.

Sure they might look legit from the outside looking in.

I won’t lie, their sales page/website is pretty damn impressive.

But the claims just don’t hold water.

Membrane Integrity Factor is a scam

If you have to resort to lying to your potential customers to make a sale, your offer is “a dishonest scheme”… the very definition of a scam.

Where to buy it?

At this point, you probably don’t want to purchase these “anti-aging” pills.

And who could blame you?!

You probably don't want to buy Membrane Integrity Factor

However, if you insist, you can buy Membrane Integrity Factor straight from the company’s website.

You can also get the product on, and other online retailers.

How much is it?

A one-month supply costs $52.49 straight from the manufacturer.If you buy on Amazon, you’re looking at about $70. That’s not cheap.

Membrane Integrity Factor costs about $55 for a one month supply

Is there a guarantee?

Yes… you can “buy with confidence,” as the company offers a 60-day 100% money-back guarantee with every membrane integrity factor purchase.

Membrane Integrity Factor offers a money-back guarantee

But notice how they change their tune here.

They market the product as an anti-aging pill, and explicitly claim that their product can essentially turn back the clock.But the guarantee says nothing about this — because they cannot guarantee it!


We’ve seen that Membrane Integrity Factor claims that it can slow the aging process and even reverse it, and help you to think more clearly.

But looking at the ingredients, we’ve highlighted all the ways that this cannot possibly be true.

The company lies in their marketing, saying that Dr. Nieper is the inventor of this anti-aging pill, and they’re far from transparent about their formula.

Anamax is filled with lies

The price is pretty outrageous for what you get, the user reviews may or may not be authentic, and there is the possibility that the pill isn’t safe to take.

All in all, Membrane Integrity Factor is a text-book scam, so I cannot recommend the product.

It’s just another product that promises the world, but delivers very little.

You’re much better off trying a so-called anti-aging product that under-promises and over-delivers.

Have you tried Membrane Integrity Factor?

Leave Your Review Below!

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Author: Rob Miller

Supplement Critique

Rob Miller founded over 7 years ago, and has been the chief editor ever since. He has a diploma in Advanced Dietary Supplements Advisor, and worked at GNC for 3 years. He KNOWS supplements, both inside and out. Rob currently resides in Jupiter, FL, with his wife of 4 years.  Learn more about him in his Bio here. Follow him on Twitter , Facebook, LinkedIn, or find him on Google +.

Medical Reviewer: Helen Okoye, MD

Dr Okoye

Dr. Helen Okoye is an American Public Health Physician, Health Care Executive, Researcher, Entrepreneur with a Doctor of Medicine Degree (MD), an MBA in Healthcare Management, and a Masters in Epidemiology/Public Health). Her specific responsibilities for Supplement Critique including reviewing previously published articles for accuracy and relevancy. Her expert opinion was featured on NBC News for the President’s physical exam. Learn more about Dr. Okoye here. Follow here on Twitter and Instagram.

15 comments on “Membrane Integrity Factor Review”

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  1. I appreciate your comments about this product it seems like a scam to me. When they talk about the German doctor they spell where he came from incorrectly for s start!!!

  2. I can tell you I have access to ultrasound technology. Studied it myself in my body.

    Had an auto renal transplant and cystectomy in 2016. A massive cut in my foot that wouldn’t heal for months.

    Performed ultrasound before I started taking it, demonstrated an almost dead right ovary from trauma and age. Hormonal decline.

    Within one week(7 days) of taking 3 pills a day which is a daily dose my cut was healed my ovary restored and fully functional again. 47.5 and still cycling normally and capable of pregnancy. I tested this product myself using my own clinical subjective physiological measurements.

    I still do CrossFit everyday. This product did help me reregulate my breathing and blood pressures post transplant.

    I’m doing great. Your review bothered me but not enough to stop taking MIF.

    I have a hard time believing at my age that my successful recovery could be anything other than MIF. I might also have thought it a scan if I had not witnessed the transformation myself.

    1. Hey Maria,
      We always look at supplements that make claims like this with a very skeptical eye, so I wouldn’t rely overwhelmingly on our comments. Glad to hear it’s working for you, and thanks for your feedback!

      1. Thanks Rob. I’m also thankful there are sites like yours that try and police products.

        I try to do as much of my own testing as possible before recommending anything. ??

    2. Rob,
      Excellent points in your article on fishy claims but having chased many supplements to help with major allergies will probably try this one as well. I have no problems returning the product if it doesnt help and will post my review.

      The other poster Beau Beard sounds like he has some stake in the product and makes the product seem even fishier. No cancer?

  3. What is the source of the anterior pituitary gland that they put in the MEMBRANE INTEGRITY FACTOR SUPPLEMENT
  4. I have studied this product for over 12 years. I have also seen the product bring 1 man literally from his death bed,(In critical care 3 1/2 months) to working in his yard without taking any of the hand full(s) of medication that he previously was taking.

    I do not see any thing here you have said that was based on any thing other than your narrow closed minded attempt(s) to argue anti aging. You apparently missed the study on the 3000 people with MS (20%) with cancer in which all 3000 were healed and without any cancer be detected.

    Anti aging? That I can’t say it does or does not do.

    But I can with 100% certainty say it will improve your quality of life. Please supply facts when you are screaming and ranting about a product that you apparently have 1 thing in mind.

    Anti aging. At least do your home work like I have for over 12 years.

    Instead of bringing bare assed allegations to prove your distain.

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